Biochemical and Ultrastructural Cardiac Changes Induced by High-Fat Diet in Female and Male Prepubertal Rabbits

Figure 7

Photomicrographs of semithin sections in the cardiac tissue of prepubertal female and male rabbits. Toluidine blue staining 100x (a, b) and 400x (c, d). Female normal-diet group (a), female high-fat diet group (b), male normal diet group (c), and male high-fat diet group (d). The cells adhere to each other in the female and male normal-diet groups (a, c, arrows) comparing to the high-fat diet groups; so under HFD effect, the cells are less contiguous. An area of focal degeneration is seen in the 2 high-fat diet groups (b, d, arrows) especially in FHFD with multiple vacuolization (V) present between the cardiomyocytes. N: nucleus; V: lipid vacuoles.

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