High HLA-F Expression Is a Poor Prognosis Factor in Patients with Nasopharyngeal Carcinoma

Table 1

Association of HLA-F expression in NPC lesions with clinicopathological parameters.

Characteristics	N	HLA-F expression
		Low	Moderate	High	value
		()	()	()
Gender
Male	52	27	17	8	0.458
Female	22	8	9	5
Age (years)
<54	37	16	12	9	0.311
≥54	37	19	14	4
Tumour differentiation
Undifferentiated	50	24	15	11	0.235
Differentiated	24	11	11	2
Tumour stage
T1 + T2	46	25	14	7	0.221
T3 + T4	27	9	12	6
Lymph node status
N0	21	12	7	2	0.389
N1–3	52	22	19	11
TNM clinical stage
I + II	24	14	5	5	0.179
III + IV	49	20	21	8
Local recurrence
No	66	33	24	9	0.037
Yes	8	2	2	4
Distant metastasis
No	64	34	21	9	0.024
Yes	10	1	5	4

Abbreviation: HLA-F: human leukocyte antigen F; TNM: tumour node metastasis.