Research Article
High HLA-F Expression Is a Poor Prognosis Factor in Patients with Nasopharyngeal Carcinoma
Table 1
Association of HLA-F expression in NPC lesions with clinicopathological parameters.
| Characteristics | N | HLA-F expression | Low | Moderate | High | value | () | () | () |
| Gender | | | | | | Male | 52 | 27 | 17 | 8 | 0.458 | Female | 22 | 8 | 9 | 5 | | Age (years) | | | | | | <54 | 37 | 16 | 12 | 9 | 0.311 | ≥54 | 37 | 19 | 14 | 4 | | Tumour differentiation | | | | | | Undifferentiated | 50 | 24 | 15 | 11 | 0.235 | Differentiated | 24 | 11 | 11 | 2 | | Tumour stage | T1 + T2 | 46 | 25 | 14 | 7 | 0.221 | T3 + T4 | 27 | 9 | 12 | 6 | | Lymph node status | | | | | | N0 | 21 | 12 | 7 | 2 | 0.389 | N1–3 | 52 | 22 | 19 | 11 | | TNM clinical stage | | | | | | I + II | 24 | 14 | 5 | 5 | 0.179 | III + IV | 49 | 20 | 21 | 8 | | Local recurrence | | | | | | No | 66 | 33 | 24 | 9 | 0.037 | Yes | 8 | 2 | 2 | 4 | | Distant metastasis | | | | | | No | 64 | 34 | 21 | 9 | 0.024 | Yes | 10 | 1 | 5 | 4 | |
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Abbreviation: HLA-F: human leukocyte antigen F; TNM: tumour node metastasis.
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