Analytical Cellular Pathology / 2018 / Article / Tab 5

Research Article

Adult Granulosa Cell Tumors of the Ovary: A Retrospective Study of 36 FIGO Stage I Cases with Emphasis on Prognostic Pathohistological Features

Table 5

Univariate analysis of disease-free survival in patients with early-stage adult granulosa cell tumors.

FeaturesNumber of documented recurrence% 5-year DFSLog-rank test (-test) value

Age (years)
 ≤55 y18294%0.624
 >55 y14283.5%
FIGO substage
 IA261100%0.0002
 IC6342%
Surgery
 Radical surgery25195%0.004
 Fertility surgery7371%
Tumor size
 <10 cm23390.5%0.860
 ≥10 cm7183.5%
Dominant growth pattern AGCT
 Diffuse14476%0.012
 Others180100%
Grade of cytologic atypia
 1150100%0.032
 2 and 317479.5%
Mitotic index
 <417294%0.736
 ≥415283.5%
LVSI
 Negative22195%0.058
 Positive10378%
Necrosis
 Absent26392%0.609
 Present6180%
Hemorrhage
 Absent23195%0.022
 Present9376%
Prominent fibrothecomatous component
 Absent22296%0.396
 Present10277%

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