Comparison of Syndecan-1 Immunohistochemical Expression in Lobular and Ductal Breast Carcinoma with Nodal Metastases

Table 4

The correlation between the Sdc1 expression in the tumor epithelium and the stroma of the total sample of both types of the primary tumors and separately of the invasive ductal and the lobular carcinomas, with various clinical and histological parameters analyzed using Spearman’s correlation coefficient.

Spearman correlation		Syndecan-1 expression in the tumor epithelium			Syndecan-1 expression in the tumor stroma
		Total sample ()	Ductal carcinoma ()	Lobular carcinoma ()	Total sample (	Ductal carcinoma ()	Lobular carcinoma ()
Age (years)	Coefficient rho	−0.159	−0.179	−0.288	−0.1	0.096	−0.346
		0.225	0.345	0.123	0.447	0.612	0.061
Tumor size (cm)	Coefficient rho	0.141	0.129	−0.021	0.242	0.114	0.28
		0.283	0.498	0.912	0.063	0.548	0.134
Focus numbers (1–3)	Coefficient rho	0.103	−0.007	0.295	−0.099	−0.139	−0.06
		0.435	0.97	0.113	0.451	0.463	0.752
Histological grade	Coefficient rho	0.228	0.185	0.078	0.187	0.000	0.442
		0.08	0.329	0.683	0.153	0.999	0.014
T status	Coefficient rho	0.023	−0.253	0.025	0.203	0.145	0.254
		0.863	0.177	0.895	0.119	0.443	0.175
N status	Coefficient rho	0.176	0.136	0.115	0.122	0.062	0.169
		0.182	0.475	0.553	0.357	0.744	0.38
Percentage of positive lymph nodes	Coefficient rho	0.213	0.254	0.071	0.002	−0.153	0.11
		0.105	0.175	0.713	0.989	0.421	0.57
ER	Coefficient rho	−0.237	−0.205	−0.268	−0.034	−0.099	0.021
		0.068	0.277	0.152	0.799	0.604	0.911
PR	Coefficient rho	−0.156	−0.442	0.187	0.022	−0.007	0.034
		0.235	0.014	0.323	0.868	0.971	0.86
HER2/neu	Coefficient rho	−0.054	−0.09	−0.052	−0.028	−0.101	0.072
		0.683	0.637	0.787	0.831	0.597	0.705