PDE4 and Epac1 Synergistically Promote Rectal Carcinoma via the cAMP Pathway

Table 3

Correlation between PDE4 and cyclin E1 protein levels in rectal cancer.

Cyclin E1	PDE4
	−	+−	+	++	+++
−	5	1	3	1	0	0.300	0.048
+−	0	2	3	3	0
+	5	2	3	0	0
++	1	0	6	2	1
+++	0	2	1	3	0

Note: is the spearman rank correlation coefficient.