Research Article
N-trans-Feruloyloctopamine Wakes Up BBC3, DDIT3, CDKN1A, and NOXA Signals to Accelerate HCC Cell Apoptosis
Figure 3
Bioinformatics analysis in FO-treated Huh7 cells. (a, b) Volcano plot of the differentially expressed genes. The thresholds were and adjusted value < 0.05. Red dots indicate upregulated genes, and blue dots indicate downregulated genes. (c) Top 20 KEGG pathways with the most enriched differentially expressed genes of RNA-Seq (). (d) Bubble plot represents the top 20 gene sets with the most enriched differential genes in the DAVID GO BP DIRECT annotation database obtained by comparing gene expression between Huh7 treated with FO and controls. The size of these bubbles represents the number of differentially expressed genes, assigned to the GO BP terms.
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