MicroRNA-21-5p Reduces Hypoxia/Reoxygenation-Induced Neuronal Cell Damage through Negative Regulation of CPEB3

Figure 5

The verification of CPEB3 as a target of miR-21-5p (). (a) CPEB3 as the target of miR-21-5p. (b) Luciferase reporter gene verification. (c) Protein expression level of CPEB3 when miR-21-5p was overexpressed in HT22 cells. (d) The expression level of CPEB3 mRNA when miR-21-5p was overexpressed in HT22 cells. The experimental groups are as follows: 1: control group; 2: H/R group; 3: NC+H/R group; 4: miR-21-5p mimic+H/R group. Note: Student’s -test was used. Compared with the control group, ^a; compared with the H/R group, ^b; compared with the NC group, ^c.

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