Research Article

“Derived Multiple Allogeneic Protein Paracrine Signaling (d-MAPPS)” Enhances T Cell-Driven Immune Response to Murine Mammary Carcinoma

Figure 4

d-MAPPS improved antigen-presenting properties of tumor-infiltrated dendritic cells. Flow cytometry analysis and intracellular staining of tumor-infiltrated (a) I-A-expressing TNF-α-producing CD11c+, (b) I-A-expressing CD11c+, (c) CD80- and CD86-expressing CD11c+, (d) IL-12-producing CD11c+, and (e) IL-10-producing CD11c+ DCs in the tumors of 4T1+saline-treated (black bars) and 4T1+d-MAPPS-treated mice (white bars). Data are presented as ( mice/group; ).
(a)
(b)
(c)
(d)
(e)