background digit stain can consid special form imag enhanc wherein concern onli increas contrast between background object object interest also impart color mark object uniqu reaction specif stain paper extend previous propos multispectr enhanc method color background pixel can also chang method previous multispectr enhanc method shift factor provid origin spectrum implement digit stain spectral transform process introduc prior spectral shift result the enhanc method appli multispectr imag stain liver tissu the result digit stain imag show good correl serialsect imag tissu which physic stain masson trichrom conclus have present multispectr enhanc method can adjust produc digit stainedimag the current experiment result show viabil method howev achiev robust enhanc perform issu aris from variat stain condit has address well this would part our futur work

Pinky A. Bautista

Yukako Yagi

Multispectral Enhancement towards Digital Staining

context virtual microscopi which diagnost work digit microscop imag tissu base diagnosi it childhood be implement routin diagnosi until today onli few patholog institut take use new technolog although avail sinc sever year whi design virtual microscopi requir new workflow organis pathologist diagnost procedur first view laboratori workflow seem remain untouch high degre howev use laboratori inform system lis which common built hierarch order has adjust it highest level diagnosi statement qualiti evalu submiss clinician hospit inform system feedback laboratori therefor laboratori workflow involv all level too lis has chang adjust requir system usual equip viewer mimic view convent microscop offer access sensit node lis similar lis usual close fix system becaus data secur certif demand thus system have possess communic access differ lis level togeth steer command lis close associ diagnost qualiti effici exampl demand addit stain immunohistochem quantit imag method etc well expert consult panel discuss outcom implement open activ lis manag system could signific promot introduct routin diagnost surgic patholog the manag system has coordin translat demand lis vice versa assur communic his mandatori featur includ stream laboratori workflow feedback command lis well regul temporari prioriti level conclus success implement system routin tissuebas diagnosi requir communic manag system long consid stand alon system just mimic convent microscop

Klaus Kayser

Stephan Borkenfeld

Gian Kayser

How to Introduce Virtual Microscopy (VM) in Routine Diagnostic Pathology: Constraints, Ideas, and Solutions

background medic educ patholog histolog lowresourc countri face mani obstacl becaus equip cost telecommun defici digit patholog may provid solut report student experi virtual slide local network remot imag server method using ipad tablet devic fifti 3rd 4th year medic student view digit patholog slide from web server nation librari medicin mirror server local network result the qualiti imag from both server found satisfactori local server deem faster prefer particip studi 0005 conclus virtual slide local network server may provid solut equip technic obstacl could enhanc student learn develop countri

Paul Fontelo

John Faustorilla

Alex Gavino

Alvin Marcelo

Digital Pathology &#x2013; Implementation Challenges in Low-Resource Countries

Marcial Garcia Rojo

Arvydas Laurinavicius

Vincenzo Della Mea

Bruce Levy

Jacques Klossa

Gary Tearney

Janus Szymas

Yasunari Tsuchihashi

Bernard Têtu

The First Congress of the International Academy of Digital Pathology: Digital Pathology Comes of Age

background the practic patholog develop world present challeng term limit resourc shortag train personnel lack continu educ program telepatholog hold promis mean diagnost educ support method donat multihead teach microscop equip digit camera four hospit eastern africa train local pathologist use static imag challeng case were post webbas telepatholog platform base pathologist review imag consult subspecialist colleagu result over period 40 month 109 case were submit second opinion consult includ 29 dermatopatholog case 266 14 hematopatholog case 128 13 case each 119 cytopatholog bone soft tissu patholog static imag enabl complet partial diagnosi 100109 case 917 factor preclud definit diagnosi includ absenc confirmatori immunophenotyp technic issu lack clinic histori case respons includ diagnosi discuss includ differenti diagnosi refer treatment recommend conclus static digit telepatholog simpl costeffect reliabl effici mean provid diagnost educ support pathologist develop world addition train may help overcom technic factor preclud definit diagnosi certain case

Aliyah R. Sohani

Moez A. Sohani

Static Digital Telepathology: A Model for Diagnostic and Educational Support to Pathologists in the Developing World

background eurotelepath european cost action ic0604 start 2007 end novemb 2011 its main object evalu valid common technolog framework communic standard requir access transmit manag digit medic record pathologist other medic specialti network environ busi model work group 1 busi model patholog has design main patholog process frozen studi formalin fix specimen studi telepatholog cytolog autopsi use busi process model notat bpmn informat standard patholog work group 2 has been dedic promot applic informat standard patholog collabor integrat healthcar enterpris ihe digit image commun medicin dicom health level seven hl7 other standard bodi conclus health terminolog standard research has becom topic great interest futur research work should focus standard automat imag analysi tissu microarray imag

Marcial García Rojo

Christel Daniel

Thomas Schrader

Standardization Efforts of Digital Pathology in Europe

background the aim eastern québec telepatholog project provid uniform diagnost telepatholog servic across huge geograph region low popul densiti this project intend provid surgeon pathologist frozen section second opinion servic anywher ani time across entir region order avoid unnecessari patient transfer method the project has been implement 21 site each equip whole slide scanner macroscopi station two videoconferenc devic viewer case manag collabor solut 21 site 6 devoid patholog laboratori remain 15 site two have pathologist 6 have one 7 have two more result the project has been success most appreci pathologist surgeon report number challeng relat chang manag had take account cours implement network the challeng underscor need regular visit activ support particip center project team conclus the eastern québec telepatholog network success improv medic care region cours implement encount number challeng which requir innov solut

Jean-Paul Fortin

Marie-Pierre Gagnon

Said Louahlia

The Challenges of Implementing a &#x201c;Patient-Oriented&#x201d; Telepathology Network; the Eastern Qu&#xe9;bec Telepathology Project Experience

for person medicin increas clinic demograph data integr nomogram prognost use while molecular biomark be develop add independ diagnost prognost manag inform number case surgic patholog morphometr quantit alreadi perform manual semiquantit effort contribut diagnost workup digit whole slide imag coupl emerg imag analysi algorithm offer great promis adjunct tool surgic pathologist area screen qualiti assur consist quantit have recent report algorithm sivq spatial invariant vector quantiz which avail itself geometr advantag ring vector pattern match have propos number potenti applic one key test howev remain need demonstr optim sivq discrimin between foreground neoplasm malign epithelium background normal parenchyma stroma vessel inflammatori cell especial import determin relat contribut each key sivq match paramet respect algorithm overal detect perform herein combinatori test sivq ring size subr number inter wobbl paramet set morpholog complex bladder cancer use case ascertain relat contribut each paramet toward overal detect optim use urotheli carcinoma use case provid exemplar which algorithm futur histologyori pattern match tool may valid subsequ implement broad other appropri microscop classif set

Jason Hipp

Steven Christopher Smith

Jerome Cheng

Scott Arthur Tomlins

James Monaco

Anant Madabhushi

Lakshmi Priya Kunju

Ulysses J. Balis

Optimization of Complex Cancer Morphology Detection Using the SIVQ Pattern Recognition Algorithm

background one goal whole slide image wsi system implement clinic practic patholog one unresolv problem accomplish goal speed entir process from view slide through make final diagnosi most user satisfi correct view speed avail system have evalu new wsi view station tool focus speed method prototyp wsi viewer base playstat 3 wireless control evalu depart patholog mgh follow reason 1 for simul signingout case 2 enabl discuss consensus confer 3 use slide seminar dure continu medic educat cours result pathologist were be abl use system comfort after 015 min train there were complaint regard speed most pathologist were satisfi function usabl speed system the most difficult situat simul diagnost signout conclus the preliminari result adapt soni playstat 3 ps3 ultrahigh speed wsi view system were promis the achiev speed consist what would need use wsi daili practic

Shigeatsu Yoshioka

Hiroshi Kyusojin

Maristela Onozato

Yoichi Mizutani

Kiyoshi Osato

Hiroaki Yada

Eugene J. Mark

Matthew P. Frosch

David N. Louis

An Ultra-High Speed Whole Slide Image Viewing System

background whole slide image wsi has been tout mani futur patholog estim full adopt occur sometim next 5 15 year while wsi devic have becom increas capabl sinc incept has been littl consider how wsi implement subsequ affect workflow high volum histolog laboratori method histolog workflow process data collect from highvolum histolog laboratori massachusett gener hospit process model develop use busi process manag softwar computer workflow simul were perform total histolog process time evalu under number differ wsi condit result total histolog process time increas approxim 10fold 20fold over baselin presenc one wsi robot histolog workflow depend specif wsi robot anywher from 9 14 wsi robot were requir within histolog workflow minim effect wsi conclus place wsi robot current workflow highvolum histolog laboratori intent full adopt feasibl implement wsi without make signific chang current workflow histolog laboratori would prove both disrupt cost surgic patholog

David S. McClintock

Roy E. Lee

John R. Gilbertson

Using Computerized Workflow Simulations to Assess the Feasibility of Whole Slide Imaging Full Adoption in a High-Volume Histology Laboratory

About this journal

Analytical Cellular Pathology provides a forum for pathologists and medical practitioners working in the cellular pathology field. Topics covered include cytology, carcinogenesis, cell receptors, biomarkers, diagnostic pathology, and immunopathology.

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Chief Editor&nbsp;Professor Dimitrios Karamichos&nbsp;focuses on investigating corneal wound healing and dystrophies with a particular interest in the effect of transforming growth factor-β3 or TGF- β3 on corneal stromal cells and their extracellular environment.

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Analytical Cellular Pathology provides a forum for pathologists and medical practitioners working in the cellular pathology field. Topics covered include cytology, carcinogenesis, cell receptors, biomarkers, diagnostic pathology, and immunopathology.

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Analytical Cellular Pathology

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