Antigen-Experienced CD4lo T Cells Are Linked to Deficient Contraction of the Immune Response in Autoimmune Diabetes
Figure 2
The expression of CD25, CD44, CD69, CD95, and CD178 is similar on NOD and BALB/c CD4+ spleen cells. Naive spleen cells or live Con A blasts (harvested by histopaque separation 72 hrs after stimulation) from groups of 3 NOD or BALB/c mice were examined individually by flow cytometry for the expression of cell surface molecules associated with activation. The data are expressed as the mean percentage of CD4+ cells (gated) that were positive for the respective molecule in groups of 3 mice, and the results are representative of 3 experiments, with at least 20,000 events collected in each experiment.
