Review Article

Juvenile Myasthenia Gravis: A Paediatric Perspective

Table 1

Comparisons of prepubertal and postpubertal features of JMG.

PrepubertalPubertalPostpubertal/
adult

Male : female ratioM = FF > M 4.5 : 1F > M 4.5 : 1

Patients with AChR antibodies detected in generalised disease50–71%
[1, 2]
68–92%
[1, 2]
80–90%

Ocular presentation
 Caucasian40% [7]  

9–16% [12]

28% [6]
 Chinese75% [6]

Progression of OMG to generalised MG8–15%
[17, 18]
23–43%
[16, 19]
79% [8]

Remission (spontaneous or with treatment)42–60%
[1, 2, 20]
26% [2]38% [9]