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Autoimmune Diseases
Volume 2012, Article ID 143813, 6 pages
Research Article

Voice-Related Quality of Life in Patients with Multiple Sclerosis

1Department of Otolaryngology-Head & Neck Surgery, American University of Beirut Medical Center, P.O. Box 11-0236, Beirut, Lebanon
2Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon
3Epidemiology and Population Health Department, American University of Beirut, Beirut, Lebanon

Received 12 June 2012; Revised 18 July 2012; Accepted 19 July 2012

Academic Editor: Ricard Cervera

Copyright © 2012 Abdul Latif Hamdan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To investigate the voice-related quality of life in a group of patients with multiple sclerosis. Participants. A total of 87 subjects (59 MS subjects and 28 controls) participated in this study. Main Outcome Measures. Variables included presence or absence of phonatory symptoms, duration of the disease, the expanded disability status scale (EDSS), the severity of fatigue, and depression. All patients were asked to fill the Voice Handicap Index. Results. The average age was 35.47 years + 10.92 with 39% being males. The average duration of the disease was 77.93 months. The EDSS score was 1.94 + 1.84, the FSS score was 4.07 + 2.09, and the HRSD was 7.28 + 7.70. Only 7 subjects out of the 59 had vocal symptoms compared to 3 in the control group. There was no significant difference in the VHI total score between cases (5.9 + 15.5) and controls (5.4 + 8.2). There was a positive correlation between VHI total score, FSS score, and HRSD (P values of 0.011 and <0.01. Conclusion. The voice-related quality of life in MS is within normal with no disability.