Research Article
Identification of TNIP1 Polymorphisms by High Resolution Melting Analysis with Unlabelled Probe: Association with Systemic Lupus Erythematosus
Table 1
Genotype and allele frequencies of TNIP1 SNPs in SLE cases and controls*.
| SNP, population | Number of subjects | Genotype frequency, (%) | value | Allele frequency, (%) | value | OR (95% CI) | Major homozygote | Heterozygote | Minor homozygote | Major allele | Minor allele |
| rs7708392 | Genotype or allele | | CC | CG | GG | | C | G | | | Cases | 283 | 179 (63.3) | 91 (32.2) | 13 (4.6) | 0.915 | 449 (79.3) | 117 (20.7) | 0.697 | 1.056 () | Controls | 336 | 207 (61.6) | 113 (33.6) | 16 (4.8) | 527 (78.4) | 145 (21.6) | rs79937737 | Genotype or allele | | GG | AG | AA | | G | A | | | Cases | 283 | 239 (84.4) | 43 (15.2) | 1 (0.4) | 0.500 | 521 (92.0) | 45 (8.0) | 0.523 | 1.148 () | Controls | 336 | 289 (86.0) | 47 (14) | 0 (0) | 625 (93.0) | 47 (7.0) |
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: single-nucleotide polymorphism; SLE: systemic lupus erythematosus; OR: odds ratios; 95% CI: 95% confidence interval.
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