Autoimmune Diseases / 2012 / Article / Tab 4

Review Article

Evaluation of ENA-6 Profile by ELISA Immunoassay in Patients with Systemic Lupus Erythematodes

Table 4

Optimal cut-off, sensitivity, specificity, positive and negative predictive value of ENA6 SM, and CIC in between SLE patients and healthy control.

SLE patients versus healthy control
MarkerOptimal
cut-off
Sensitivity (%)Specificity (%)Positive predictive
value (%)
Negative predictive value (%)

Sm/RNP≥8,33 EU75%100%100%81%
Jo-1≥1,005 EU83%90%89%84%
SCL-70≥0,385 EU96%80%83%96%
ENA6 Sm≥9,56 EU70%100%100%76%
ENA6 SS-A≥5,90 EU64%76%72%69%
ENA6 SS-B≥5,44 EU60%73%69%65%

SLE: systemic lupus erythematosus; EU: elisa units.

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