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Autoimmune Diseases
Volume 2012 (2012), Article ID 736384, 7 pages
Clinical Study

Spondyloarthropathies in Autoimmune Diseases and Vice Versa

1Center for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario, Carrera 24 # 63-C-69, Bogotá, Colombia
2Rheumatology Unit, Riesgo de Fractura-CAYRE IPS, Bogotá, Colombia

Received 15 October 2011; Revised 22 November 2011; Accepted 30 November 2011

Academic Editor: Mario García-Carrasco

Copyright © 2012 Oscar M. Pérez-Fernández et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Polyautoimmunity is one of the major clinical characteristics of autoimmune diseases (ADs). The aim of this study was to investigate the prevalence of ADs in spondyloarthropathies (SpAs) and vice versa. This was a two-phase cross-sectional study. First, we examined the presence of ADs in a cohort of patients with SpAs ( ). Second, we searched for the presence of SpAs in a well-defined group of patients with ADs ( ) including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and Sjögren’s syndrome (SS). Among patients with SpAs, ankylosing spondylitis was observed in the majority of them (55.6%). There were two patients presenting with SS in the SpA group (1.4%) and 5 patients with autoimmune thyroiditis (3.5%). The global prevalence of ADs in SpAs was 4.86%. In the ADs group, there were 5 patients with SpAs (0.46%). Our results suggest a lack of association between SpAs and ADs. Accordingly, SpAs might correspond more to autoinflammatory diseases rather than to ADs.