Multiple Autoantibodies Display Association with Lymphopenia, Proteinuria, and Cellular Casts in a Large, Ethnically Diverse SLE Patient Cohort

Table 2

Univariate conditional logistic regression models within European-American, African-American, and Hispanic populations using ACR SLE criteria or subcriteria as the outcome and individual autoantibodies and sex as covariates.

Criteria/subcriteria	Covariates	European American		African American		Hispanic
		Odds ratio (95% CI)	𝑃 value	Odds ratio (95% CI)	𝑃 value	Odds ratio (95% CI)	𝑃 value
	60 kD Ro	3.19 (1.55, 6.56)	0.0016
	La	3.84 (1.43, 10.33)	0.0076
Hematological disorder	52 kD Ro	2.99 (1.26, 7.07)	0.0128
	Sm/RNP	2.28 (1.11, 4.70)	0.0257	2.64 (1.09, 6.37)	0.0315
	RNP 68	3.92 (1.08, 14.27)	0.0379
	RNP A					11.93 (1.53, 93.37)	0.0182
	52 kD Ro	2.10 (1.00, 4.38)	0.0489
Leukopenia	Ribo P	3.77 (1.22, 11.60)	0.0207	3.16 (1.25, 8.00)	0.0154
	Sm			2.31 (1.33, 6.31)	0.0072
	60 kD Ro	2.26 (1.24, 4.15)	0.0082
	52 kD Ro	2.78 (1.33, 5.79)	0.0064	2.90 (1.33, 6.31)	0.0072
Lymphopenia	RNP 68	4.72 (1.30, 17.11)	0.0182			8.62 (1.05, 71.00)	0.0452
	RNP A					3.89 (1.07, 14.17)	0.0391
	Chromatin					3.13 (1.09, 8.97)	0.0334
	Sm/RNP					3.27 (1.09, 9.78)	0.0340
Hemolytic anemia	Chromatin					0.10 (0.01, 0.95)	0.0446
Renal disease	dsDNA			2.38 (1.15, 4.94)	0.0197
Proteinuria	La	0.37 (0.15, 0.91)	0.0293
	Sex			1.97 (1.04, 3.71)	0.0368
	dsDNA			3.69 (1.46, 9.32)	0.0058
Cellular casts	Chromatin			2.90 (1.27, 6.59)	0.0113
	Sm/RNP			3.65 (1.55, 8.64)	0.0032
Oral ulcer	Sm/RNP			1.97 (1.04, 3.71)	0.0368
Photosensitivity	52 kD Ro			0.38 (0.16, 0.92)	0.0329
	Sex	2.30 (1.00, 5.29)	0.0492
Malar rash	La	0.43 (0.21, 0.89)	0.0234
	Sex	3.17 (1.37, 7.33)	0.0069