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Autoimmune Diseases
Volume 2013, Article ID 103081, 6 pages
Review Article

Laryngeal Manifestations of Rheumatoid Arthritis

Department of Otolaryngology-Head & Neck Surgery, American University of Beirut Medical Center, P.O. Box 11-0236, Beirut, Lebanon

Received 1 March 2013; Accepted 23 May 2013

Academic Editor: Daniela Melchiorre

Copyright © 2013 A. L. Hamdan and D. Sarieddine. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Rheumatoid arthritis is a destructive autoimmune disease that affects 3% of the adult population. It is characterized by the formation of both articular and extra-articular lesions with predilection for small joints. There are ubiquitous reports on the head and neck manifestations of RA with emphasis on the larynx. The laryngeal presenting features of this systemic disease may mimic a plethora of medical conditions, inflammatory and neoplastic. The main phonatory and respiratory symptoms are often subtle and misleading. This paper represents a literature review of the laryngeal manifestations of RA with emphasis on the clinical symptoms, laryngeal findings, diagnosis, and treatment. An early diagnosis of laryngeal involvement may prevent drastic complications.