Lower Serum Androstenedione Levels in Pre-Rheumatoid Arthritis versus Normal Control Women: Correlations with Lower Serum Cortisol Levels

Table 4

Age-adjusted, log-normalized correlations (Pearson) of hormones in lower-level cortisol pre-RA (top) and CN (bottom) females*.

Hormones		Preg	Prog	17-OHpreg	17-OHprog	DHEA	Adione	Test	Estradiol	Estrone	Cmpd B	DeoxyCort	Cortisol	DHEAS
Preg	𝑟		0.456	0.179	0.498	0.505	0.442	−0.099	0.489	−0.797	0.418	0.639	0.256	0.662
	𝑝		0.217	0.645	0.173	0.165	0.273	0.800	0.182	0.203	0.263	0.064	0.507	0.052
	𝑛		10	10	10	10	9	10	10	5	10	10	10	10
Prog	𝑟	0.654		0.354	0.712	0.354	0.268	−0.447	0.084	−0.080	0.098	0.658	−0.332	0.665
	𝑝	0.000		0.350	0.031	0.350	0.521	0.228	0.831	0.920	0.775	0.028	0.319	0.026
	𝑛	54		10	10	10	9	10	10	5	12	12	12	12
17-OHpreg	𝑟	0.332	0.285		0.690	0.369	0.571	−0.349	0.336	0.498	−0.019	0.469	−0.130	0.163
	𝑝	0.015	0.039		0.040	0.328	0.139	0.358	0.376	0.502	0.962	0.202	0.738	0.676
	𝑛	54	54		10	10	9	10	10	5	10	10	10	10
17-OHprog	𝑟	0.593	0.729	0.727		0.506	0.656	−0.347	0.536	0.105	0.142	0.860 ^†	−0.143	0.393
	𝑝	0.000	0.000	0.000		0.164	0.077	0.360	0.136	0.895	0.716	0.003	0.713	0.295
	𝑛	54	54	54		10	9	10	10	5	10	10	10	10
DHEA	𝑟	0.075	0.014	0.664	0.369		0.534	0.512	0.306	−0.029	0.300	0.734	0.077	0.555
	𝑝	0.600	0.922	0.000	0.008		0.173	0.159	0.423	0.971	0.432	0.024	0.844	0.121
	𝑛	52	52	52	52		9	10	10	5	10	10	10	10
Adione	𝑟	0.073	0.077	0.462	0.376	0.796		0.286	0.825	−0.042	0.806	0.782 *	0.159	0.212
	𝑝	0.606	0.589	0.001	0.006	0.000		0.493	0.012	0.958	0.016	0.022	0.707	0.614
	𝑛	50	53	53	53	52		9	9	5	9	9	9	9
Test	𝑟	0.067	−0.234	0.282	0.037	0.447	0.377		−0.037	−0.153	0.198	0.021	0.096	−0.113
	𝑝	0.643	0.103	0.047	0.801	0.001	0.007		0.925	0.847	0.609	0.958	0.805	0.773
	𝑛	48	51	51	51	50	51		10	5	10	10	10	10
Estradiol	𝑟	0.275	0.373	0.287	0.421	0.024	0.012	−0.039		−0.033	0.643	0.553	0.357	0.023
	𝑝	0.051	0.007	0.041	0.002	0.871	0.935	0.791		0.967	0.062	0.122	0.345	0.954
	𝑛	49	52	52	52	50	51	49		5	10	10	10	10
Estrone	𝑟	0.124	−0.030	−0.201	−0.227	−0.194	−0.066	−0.064	0.337		−0.562	−0.155	−0.212	−0.455
	𝑝	0.539	0.883	0.315	0.256	0.353	0.748	0.765	0.086		0.438	0.845	0.788	0.545
	𝑛	25	28	28	28	26	27	25	28		5	5	5	5
Cmpd B	𝑟	0.256	0.036	0.155	0.150	−0.026	0.041	0.112	0.013	−0.248		0.397	0.604	0.231
	𝑝	0.064	0.768	0.268	0.283	0.858	0.773	0.441	0.926	0.212		0.227	0.049	0.493
	𝑛	54	71	54	54	52	53	51	52	28		12	12	12
DeoxyCort	𝑟	0.340	0.207	0.207	0.173	0.077	−0.017	0.168	0.082	−0.254	0.408		−0.031	0.561
	𝑝	0.013	0.086	0.137	0.215	0.590	0.903	0.242	0.568	0.202	0.000		0.929	0.073
	𝑛	54	71	54	54	52	53	51	52	28	72		12	12
Cortisol	𝑟	−0.267	−0.313	0.087	−0.151	0.180	0.127	0.078	−0.205	0.222	−0.012	−0.136		−0.144
	𝑝	0.053	0.008	0.534	0.280	0.207	0.369	0.590	0.149	0.265	0.922	0.259		0.673
	𝑛	54	71	54	54	52	53	51	52	28	72	72		12
DHEAS	𝑟	0.278	0.192	0.535	0.297	0.436	0.299	0.144	0.079	−0.077	0.107	0.082	−0.065
	𝑝	0.044	0.111	0.000	0.031	0.001	0.031	0.318	0.579	0.703	0.372	0.495	0.593
	𝑛	54	71	54	54	52	53	51	52	28	72	72	72

∗Significant differences between pre-RA versus CN correlations, when requiring both adjusted and set-specific Z-score values to combine assay results.
Symbols placed at the greater 𝑟 values: ^∗𝑃≤0.050; ^†𝑃≤0.010.