NETosis

Table 1

Cell death.

Morphological criteria: dead cell	Point of no return: dying cell
Loss of plasma membrane integrity	Massive activation of caspases (present also in differentiation and activation of cells)
Cell fragmentation	Mitochondrial transmembrane permeabilization
Engulfment by adjacent cells	Mitochondrial membrane permeabilization (with leak of catabolic enzymes or enzymatic activators)
	Exposure of phosphatidylserine in the outer membrane (could be a transient process, e.g., T-cell activation)