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Autoimmune Diseases
Volume 2013, Article ID 827254, 17 pages
http://dx.doi.org/10.1155/2013/827254
Review Article

B Lymphocytes: Development, Tolerance, and Their Role in Autoimmunity—Focus on Systemic Lupus Erythematosus

Department of Internal Medicine, Division of Rheumatology, Fundación Valle del Lili, ICESI University School of Medicine, Cra 98 No. 18-49, Cali, Colombia

Received 30 June 2013; Accepted 6 August 2013

Academic Editor: Juan-Manuel Anaya

Copyright © 2013 Gabriel J. Tobón et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [33 citations]

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  • B. Oliviero, S. Mantovani, S. Ludovisi, S. Varchetta, D. Mele, S. Paolucci, F. Baldanti, and M. U. Mondelli, “Skewed B cells in chronic hepatitis C virus infection maintain their ability to respond to virus-induced activation,” Journal of Viral Hepatitis, 2014. View at Publisher · View at Google Scholar
  • Isharat Yusuf, Jessica Stern, Tom M. McCaughtry, Sandra Gallagher, Hong Sun, Changshou Gao, Thomas Tedder, Gianluca Carlesso, Laura Carter, Ronald Herbst, and Yue Wang, “Germinal Center B Cell Depletion Diminishes CD4(+) Follicular T Helper Cells in Autoimmune Mice,” Plos One, vol. 9, no. 8, 2014. View at Publisher · View at Google Scholar
  • Hannah Beckwith, and Liz Lightstone, “Rituximab in systemic lupus erythematosus and lupus nephritis,” Nephron - Clinical Practice, vol. 128, pp. 250–254, 2014. View at Publisher · View at Google Scholar
  • Ting Zhao, Yongqing Li, Baoling Liu, Roderick T. Bronson, Ihab Halaweish, and Hasan B. Alam, “Histone deacetylase III as a potential therapeutic target for the treatment of lethal sepsis,” Journal Of Trauma And Acute Care Surgery, vol. 77, no. 6, pp. 913–919, 2014. View at Publisher · View at Google Scholar
  • Yuki Ishikawa, Takashi Usui, Aoi Shiomi, Masakazu Shimizu, Kosaku Murakami, and Tsuneyo Mimori, “Functional engraftment of human peripheral T and B cells and sustained production of autoantibodies in NOD/LtSzscid/IL-2R gamma(-/-) mice,” European Journal of Immunology, vol. 44, no. 11, pp. 3453–3463, 2014. View at Publisher · View at Google Scholar
  • Serena Bugatti, Barbara Vitolo, Roberto Caporali, Carlomaurizio Montecucco, and Antonio Manzo, “B Cells in Rheumatoid Arthritis: From Pathogenic Players to Disease Biomarkers,” Biomed Research International, 2014. View at Publisher · View at Google Scholar
  • Panagiotis Pateinakis, and Athina Pyrpasopoulou, “CD20+B Cell Depletion in Systemic Autoimmune Diseases: Common Mechanism of Inhibition or Disease-Specific Effect on Humoral Immunity?,” Biomed Research International, 2014. View at Publisher · View at Google Scholar
  • Jordan C. Achtman, and Victoria P. Werth, “Pathophysiology of cutaneous lupus erythematosus,” Arthritis Research & Therapy, vol. 17, 2015. View at Publisher · View at Google Scholar
  • Chaojun Hu, Wei Huang, Hua Chen, Guang Song, Ping Li, Qiang Shan, Xuan Zhang, Fengchun Zhang, Heng Zhu, Lin Wu, and Yongzhe Li, “Autoantibody Profiling on Human Proteome Microarray for Biomarker Discovery in Cerebrospinal Fluid and Sera of Neuropsychiatric Lupus,” Plos One, vol. 10, no. 5, 2015. View at Publisher · View at Google Scholar
  • Soomro Sanam, Krause Kate, Yong Du, and Chandra Mohan, “Animal models of lupus and lupus nephritis,” Current Pharmaceutical Design, vol. 21, no. 18, pp. 2320–2349, 2015. View at Publisher · View at Google Scholar
  • Gamal Badr, Ayat Sayed, Mostafa A. Abdel-Maksoud, Amany O. Mohamed, Azza El-Amir, Fathy A. Abdel-Ghaffar, Saleh Al-Quraishy, and Mohamed H. Mahmoud, “Infection of Female BWF1 Lupus Mice with Malaria Parasite Attenuates B Cell Autoreactivity by Modulating the CXCL12/CXCR4 Axis and Its Downstream Sign,” Plos One, vol. 10, no. 4, 2015. View at Publisher · View at Google Scholar
  • Hiroto Tsuboi, Isao Matsumoto, Shinya Hagiwara, Tomoya Hirota, Hiroyuki Takahashi, Hiroshi Ebe, Masahiro Yokosawa, Chihiro Hagiya, Hiromitsu Asashima, Chinatsu Takai, Haruka Miki, Naoto Umeda, Yuya Kondo, Hiroshi Ogishima, Takeshi Suzuki, Shintaro Hirata, Kazuyoshi Saito, Yoshiya Tanaka, Yoshiro Horai, Hideki Nakamura, Atsushi Kawakami, and Takayuki Sumida, “Efficacy and safety of abatacept for patients with Sjogren's syndrome associated with rheumatoid arthritis: Rheumatoid Arthritis with Orencia Trial to,” Modern Rheumatology, vol. 25, no. 2, pp. 187–193, 2015. View at Publisher · View at Google Scholar
  • Wen-Juan Li, Jia-Qi Zou, Xin-Xin Han, Zhi-Hui Tian, Jie Liu, and Hai-Dong Li, “Purification and culture methods of murine splenic B-lymphocytes,” Chinese Journal of Tissue Engineering Research, vol. 19, no. 2, pp. 207–212, 2015. View at Publisher · View at Google Scholar
  • T. Zhao, H. B. Alam, B. Liu, R. T. Bronson, V. C. Nikolian, E. Wu, W. Chong, and Y. Li, “Selective Inhibition of SIRT2 Improves Outcomes in a Lethal Septic Model,” Current Molecular Medicine, vol. 15, no. 7, pp. 634–641, 2015. View at Publisher · View at Google Scholar
  • Francisca M. Vera, Juan M. Manzaneque, Francisco M. Rodriguez, Rebecca Bendayan, Nieves Fernandez, and Antonio Alonso, “Acute Effects on the Counts of Innate and Adaptive Immune Response Cells After 1 Month of Taoist Qigong Practice,” International Journal Of Behavioral Medicine, vol. 23, no. 2, pp. 198–203, 2016. View at Publisher · View at Google Scholar
  • Anand Rotte, Madhuri Bhandaru, Anand Rotte, and Madhuri Bhandaru, “Overview of Immune System,” Immunotherapy of Melanoma, pp. 113–142, 2016. View at Publisher · View at Google Scholar
  • Madhuri Bhandaru, and Anand Rottepp. 1–434, 2016. View at Publisher · View at Google Scholar
  • Aparna Gomes, Antony Gomes, Jayeeta Sengupta, Poulami Datta, and Sourav Ghosh, “Physiological interactions of nanoparticles in energy metabolism, immune function and their biosafety: A review,” Journal of Nanoscience and Nanotechnology, vol. 16, no. 1, pp. 92–116, 2016. View at Publisher · View at Google Scholar
  • Peter Pietschmann, Diana Mechtcheriakova, Anastasia Meshcheryakova, Ursula Foeger-Samwald, and Isabella Ellinger, “Immunology of Osteoporosis: A Mini-Review,” Gerontology, vol. 62, no. 2, pp. 128–137, 2016. View at Publisher · View at Google Scholar
  • Marzena Garley, Andrzej Szpak, Jolanta Sawicka-Powierza, Jarosław Piszcz, Magdalena Kakareko, Wioletta Ratajczak-Wrona, Angelika Charkiewicz, Ewa Jabłońska, Janusz Kłoczko, and Wioleta Omeljaniuk, “Expression of IL-1 and IL-6 and their natural regulators in leukocytes of B-cell chronic lymphocytic leukaemia patients,” Advances in Medical Sciences, vol. 61, no. 2, pp. 187–192, 2016. View at Publisher · View at Google Scholar
  • D. Oleksyn, J. Zhao, A. Vosoughi, J.C. Zhao, R. Misra, A.P. Pentland, D. Ryan, J. Anolik, C. Ritchlin, J. Looney, A.P. Anandarajah, G. Schwartz, L.M. Calvi, M. Georger, C. Mohan, I. Sanz, and L. Chen, “PKK deficiency in B cells prevents lupus development in Sle lupus mice,” Immunology Letters, vol. 185, pp. 1–11, 2017. View at Publisher · View at Google Scholar
  • Saheli Sadanand, and Mary M. Tomaykopp. 97–119, 2017. View at Publisher · View at Google Scholar
  • Feng Zhang, Jin-Ling Shu, Ying Li, Yu-Jing Wu, Xian-Zheng Zhang, Le Han, Xiao-Yu Tang, Chen Wang, Qing-Tong Wang, Jing-Yu Chen, Yan Chang, Hua-Xun Wu, Ling-Ling Zhang, and Wei Wei, “CP-25, a Novel Anti-inflammatory and Immunomodulatory Drug, Inhibits the Functions of Activated Human B Cells through Regulating BAFF and TNF-alpha Signaling and Comparative Efficacy with Biological Agents,” Frontiers in Pharmacology, vol. 8, 2017. View at Publisher · View at Google Scholar
  • J. Monserrat Sanz, A.M. Gómez Lahoz, L. Paule Peral, and A. Prieto Martín, “Componentes celulares y organización tisular del sistema inmune adaptativo,” Medicine - Programa de Formación Médica Continuada Acreditado, vol. 12, no. 24, pp. 1379–1387, 2017. View at Publisher · View at Google Scholar
  • Yan Cao, Wensong Zhang, Jie Wu, Hong Zhang, and Hongyan Zhou, “Peripheral Ulcerative Keratitis Associated with Autoimmune Disease: Pathogenesis and Treatment,” Journal of Ophthalmology, vol. 2017, pp. 1–12, 2017. View at Publisher · View at Google Scholar
  • Svobodová, and Štourač, “The role of the cell-mediated immunity in the pathogenesis of multiple sclerosis with focus on Th17 and treg lymfocytes,” Ceska a Slovenska Neurologie a Neurochirurgie, vol. 80, no. 2, pp. 173–179, 2017. View at Publisher · View at Google Scholar
  • Patrick K A Kearns, Helen A Casey, and John Paul Leach, “Hypothesis: Multiple sclerosis is caused by three-hits, strictly in order, in genetically susceptible persons,” Multiple Sclerosis and Related Disorders, vol. 24, pp. 157–174, 2018. View at Publisher · View at Google Scholar
  • Gregory J. Opiteck, Bryan Clemons, Robert Peach, Fiona L. Scott, Kristen R. Taylor Meadows, Marcos W. Steinberg, and Matthew E. Stokes, “Ozanimod (RPC1063), a selective S1PR1 and S1PR5 modulator, reduces chronic inflammation and alleviates kidney pathology in murine systemic lupus erythematosus,” PLoS ONE, vol. 13, no. 4, 2018. View at Publisher · View at Google Scholar
  • Chen-xing Zhang, Ji Chen, Li Cai, Jing Wu, Jia-yuan Wang, Lan-fang Cao, Wei Zhou, and Tong-xin Chen, “DNA induction of MDM2 promotes proliferation of human renal mesangial cells and alters peripheral B cells subsets in pediatric systemic lupus erythematosus,” Molecular Immunology, vol. 94, pp. 166–175, 2018. View at Publisher · View at Google Scholar
  • Ini-Isabée Witzel, Rasha Nasser, Anna Garcia-Sabaté, Jiranuwat Sapudom, Chao Ma, Weiqiang Chen, and Jeremy C. M. Teo, “Deconstructing Immune Microenvironments of Lymphoid Tissues for Reverse Engineering,” Advanced Healthcare Materials, pp. 1801126, 2018. View at Publisher · View at Google Scholar
  • Tomasz Przybyla, Tadeusz Pawelczyk, and Monika Sakowicz-Burkiewicz, “Purinergic signaling in B cells,” Acta Biochimica Polonica, vol. 65, no. 1, pp. 1–7, 2018. View at Publisher · View at Google Scholar
  • S. V. Chulkova, E. N. Sholokhova, N. V. Grishchenko, D. A. Ryabchikov, L. Y. Grivtsova, I. S. Bazin, and N. N. Tupitsyn, “The role of B-1 lymphocytes in antitumor immunity in patients with gastric cancer,” Russian Journal of Biotherapy, vol. 17, no. 4, pp. 64–70, 2019. View at Publisher · View at Google Scholar
  • Lei Zhang, Jun Yu, Chun Wang, and Wei Wei, “The effects of total glucosides of paeony (TGP) and paeoniflorin (Pae) on inflammatory-immune responses in rheumatoid arthritis (RA),” Functional Plant Biology, vol. 46, no. 2, pp. 107, 2019. View at Publisher · View at Google Scholar