B Lymphocytes: Development, Tolerance, and Their Role in Autoimmunity—Focus on Systemic Lupus Erythematosus

<table>BAFF receptor cell surface expression and self-tolerance during B cell ontogenesis. Data indicate the proportion of self-reactive B cells at specific B cell stages before or after checkpoints as determined in the anti-HEL/HEL transgenic models. Fo: follicular; GC: germinal center; Imm: immature; MZ: marginal zone; Pre: precursor; T1 or 2: transitional type 1 or 2. </table>

Autoimmune Diseases

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Figure 8

Figure 8: B Lymphocytes: Development, Tolerance, and Their Role in Autoimmunity—Focus on Systemic Lupus Erythematosus 