Prevalence of Thyroid Autoimmunity in Children with Celiac Disease Compared to Healthy 12-Year Olds

Table 1

Risk for thyroid peroxidase antibody (TPO) positivity in 12-year olds when comparing treated and untreated celiac disease (CD) cases with non-CD children through a case-referent study nested within the ETICS¹ study.

Groups	TPO^2				OR^3	95% CI^3
	Positive (𝑛=72)		Negative (𝑛=1958)
	𝑛	%^4	𝑛	%
Non-CD^5	48	2.8	1647	97.2	1.0	—
Previously diagnosed CD	7	7.5	86	92.5	2.8	1.2–6.4
Screening-detected CD	17	7.0	225	93.0	2.6	1.5–4.6

1Exploring the Iceberg of celiacs in Sweden (ETICS).
2The thyroid peroxidase (TPO) cut-off used was 100 U/mL.
3Logistic regression was used to estimate odds ratio (OR) with 95% confidence interval (CI).
4Row percentages.
5Children not diagnosed with celiac disease (CD).