Review Article

A Potential Link between Environmental Triggers and Autoimmunity

Figure 12

High-salt diet increases risk of autoimmune disease. In two groups of mice, both of which were immunized with MOG to induce EAE, the mice that had been given a high-salt diet (HSD) showed enhanced differentiation of naïve T cells into pathogenic TH17 cells and a subsequent increased, more profligate development of EAE.
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