Review Article
A Potential Link between Environmental Triggers and Autoimmunity
Table 3
Examples of bacterial and viral antigens that can cross-react with self-antigens with potentially resultant diseases.
| Pathogen antigen | Cross-reactive self-antigen | Autoimmune disease |
| Herpes simplex virus | Corneal antigen | Stromal keratitis | Campylobacter jejuni | Ganglioside in peripheral nerve | Guillain-Barré syndrome | Coxsackievirus | Glutamic acid decarboxylase | Type 1 diabetes | Theiler’s murine encephalomyelitis virus | Proteolipid protein | Multiple sclerosis | Yersinia enterocolitica | Thyrotropin receptor | Thyroid autoimmunity | Borrelia burgdorferi | Leukocyte function associated antigen | Lyme arthritis | Salmonella typhi and Yersinia enterocolitica | HLA-B27 | Reactive arthritis | HHV-6, EBV, Rubeolla, influenza virus, and HPV | Myelin basic protein | Multiple sclerosis | Streptococcal M protein | Myosin and other heart valve proteins | Rheumatic fever | Trypanosoma cruzi | Cardiac myosis | Chagas heart disease |
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