Serum Leptin Levels in Treatment-Naive Patients with Clinically Isolated Syndrome or Relapsing-Remitting Multiple Sclerosis

Table 3

Multiple regression analyses with dependent variable ratio leptin/BMI, an index of adipocyte leptin secreting activity in therapy-naïve male and female MS patients. CIS: clinically isolated syndrome; RR: relapsing-remitting MS; duration of illness in months; OB: oligoclonal bands in CSF; GEL: gadolinium enhanced lesions in MRI; EDSS: score in the expanded disability status scale.

	Males		Females, all		CIS-females		RR-females
	.2551		.4503		.3881		.6693
	0.40		2.44		0.92		2.60
	.84		.047		.748		.06
Variable	Beta		Beta		Beta		Beta
Duration	−0.070	.71	0.394	.007	−0.230	.25	0.671	.004
Relapse	−0.1796	.36	−0.189	.29	−0.449	.09	0.159	.56
OB	−0.014	.94	0.024	.86	.108	.61	−0.054	.78
GEL	0.230	.23	−0.101	.49	−0.096	.65	−0.176	.42
EDSS	0.001	.99	0.148	.39	0.295	.22	−0.222	.41