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Autoimmune Diseases
Volume 2014 (2014), Article ID 962530, 5 pages
http://dx.doi.org/10.1155/2014/962530
Clinical Study

Intravenous Immunoglobulin Treatment in Chronic Neurological Diseases: Do We Have Maintenance Dose Right?

NHS Scotland, Dumfries and Galloway Royal Infirmary, Bankend Road, Dumfries DG14AP, UK

Received 22 September 2014; Accepted 30 November 2014; Published 18 December 2014

Academic Editor: Ricard Cervera

Copyright © 2014 Ondrej Dolezal. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. Kondo, K. Kasahara, T. Kameyama et al., “Intravenous immunoglobulins suppress immunoglobulin productions by suppressing Ca2+-dependent signal transduction through FCγ receptors in B lymphocytes,” Scandinavian Journal of Immunology, vol. 40, no. 1, pp. 37–42, 1994. View at Publisher · View at Google Scholar · View at Scopus
  2. M. D. Kazatchkine, G. Dietrich, V. Hurez et al., “V region-mediated selection of autoreactive repertoires by intravenous immunoglobulin (i.v.Ig),” Immunological Reviews, vol. 139, pp. 79–107, 1994. View at Google Scholar · View at Scopus
  3. M. D. Kazatchkine and S. V. Kaveri, “Immunomodulation of autoimmune and inflammatory diseases with intravenous immune globulin,” The New England Journal of Medicine, vol. 345, no. 10, pp. 747–755, 2001. View at Publisher · View at Google Scholar · View at Scopus
  4. S. Lacroix-Desmazes, S. V. Kaveri, L. Mouthon et al., “Self-reactive antibodies (natural autoantibodies) in healthy individuals,” Journal of Immunological Methods, vol. 216, no. 1-2, pp. 117–137, 1998. View at Publisher · View at Google Scholar · View at Scopus
  5. O. Aktas, S. Waiczies, U. Grieger, U. Wendling, R. Zschenderlein, and F. Zipp, “Polyspecific immunoglobulins (IVIg) suppress proliferation of human (auto)antigen-specific T cells without inducing apoptosis,” Journal of Neuroimmunology, vol. 114, no. 1-2, pp. 160–167, 2001. View at Publisher · View at Google Scholar · View at Scopus
  6. P. L. Masson, “Elimination of infectious antigens and increase of IgG catabolism as possible modes of action of IVIg,” Journal of Autoimmunity, vol. 6, no. 6, pp. 683–689, 1993. View at Publisher · View at Google Scholar · View at Scopus
  7. C. Ritter, D. Forster, P. Albrecht, H. P. Hartung, B. C. Kieseier, and H. C. Lehmann, “IVIG regulates BAFF expression in patients with chronic inflammatory demyelinating polyneuropathy (CIDP),” Journal of Neuroimmunology, vol. 274, no. (1-2), pp. 225–229, 2014. View at Google Scholar
  8. K. Asakura, D. J. Miller, K. Murray, R. Bansal, S. E. Pfeiffer, and M. Rodriguez, “Monoclonal autoantibody SCH94.03, which promotes central nervous system remyelination, recognizes an antigen on the surface of oligodendrocytes,” Journal of Neuroscience Research, vol. 43, no. 3, pp. 273–281, 1996. View at Google Scholar
  9. K. Asakura, R. J. Pogulis, L. R. Pease, and M. Rodriguez, “A monoclonal autoantibody which promotes central nervous system remyelination is highly polyreactive to multiple known and novel antigens,” Journal of Neuroimmunology, vol. 65, no. 1, pp. 11–19, 1996. View at Publisher · View at Google Scholar · View at Scopus
  10. M. Stangel, A. Compston, and N. J. Scolding, “Oligodendroglia are protected from antibody-mediated complement injury by normal immunoglobulins (“IVIg”),” Journal of Neuroimmunology, vol. 103, no. 2, pp. 195–201, 2000. View at Publisher · View at Google Scholar · View at Scopus
  11. P. J. Dyck, W. J. Litchy, K. M. Kratz et al., “A plasma exchange versus immune globulin infusion trial in chronic inflammatory demyelinating polyradiculoneuropathy,” Annals of Neurology, vol. 36, no. 6, pp. 838–845, 1994. View at Publisher · View at Google Scholar · View at Scopus
  12. F. Eftimov, J. B. Winer, M. Vermeulen, R. de Haan, and I. N. van Schaik, “Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy,” The Cochrane Database of Systematic Reviews, no. 1, Article ID CD001797, 2009. View at Publisher · View at Google Scholar
  13. A. F. Hahn, C. F. Bolton, D. Zochodne, and T. E. Feasby, “Intravenous immunoglobulin treatment in chronic inflammatory demyelinating polyneuropathy. A double-blind, placebo-controlled, cross-over study,” Brain, vol. 119, no. 4, pp. 1067–1077, 1996. View at Publisher · View at Google Scholar · View at Scopus
  14. J. R. Mendell, R. J. Barohn, M. L. Freimer, and tal, “Randomized controlled trial of IVIg in untreated chronic inflammatory demyelinating polyradiculoneuropathy,” Neurology, vol. 56, no. 4, pp. 445–449, 2001. View at Publisher · View at Google Scholar · View at Scopus
  15. M. Jinka and V. Chaudhry, “Treatment of multifocal motor neuropathy,” Current Treatment Options in Neurology, vol. 16, no. 2, article 269, 2014. View at Publisher · View at Google Scholar · View at Scopus
  16. M. Vermeulen, “Is intravenous administration of immunoglobulins a first-choice method in autoimmune diseases?” Nederlands Tijdschrift voor Geneeskunde, vol. 137, no. 39, pp. 1955–1958, 1993. View at Google Scholar
  17. R. A. C. Hughes, P. Donofrio, V. Bril et al., “Intravenous immune globulin (10% caprylate-chromatography purified) for the treatment of chronic inflammatory demyelinating polyradiculoneuropathy (ICE study): a randomised placebo-controlled trial,” The Lancet Neurology, vol. 7, no. 2, pp. 136–144, 2008. View at Publisher · View at Google Scholar · View at Scopus
  18. J.-M. Léger, J. L. De Bleecker, C. Sommer et al., “Efficacy and safety of Privigen in patients with chronic inflammatory demyelinating polyneuropathy: results of a prospective, single-arm, open-label Phase III study (the PRIMA study),” Journal of the Peripheral Nervous System, vol. 18, no. 2, pp. 130–140, 2013. View at Publisher · View at Google Scholar · View at Scopus
  19. A. Baumann, C. W. Hess, and M. Sturzenegger, “IVIg dose increase in multifocal motor neuropathy,” Journal of Neurology, vol. 256, no. 4, pp. 608–614, 2009. View at Publisher · View at Google Scholar · View at Scopus
  20. R. Broyles, L. Rodden, P. Riley, and M. Berger, “Variability in intravenous immunoglobulin G regimens for autoimmune neuromuscular disorders,” Postgraduate Medicine, vol. 125, no. 2, pp. 65–72, 2013. View at Publisher · View at Google Scholar · View at Scopus
  21. P. Gajdos, “Intravenous immune globulin in myasthenia gravis,” Clinical and Experimental Immunology, Supplement, vol. 97, supplement 1, pp. 49–51, 1994. View at Google Scholar · View at Scopus
  22. Joint Task Force of the EFNS and the PNS, “European Federation of Neurological Societies/Peripheral Nerve Society guideline on management of multifocal motor neuropathy. Report of a joint task force of the European Federation of Neurological Societies and the Peripheral Nerve Society—first revision,” Journal of the Peripheral Nervous System, vol. 15, no. 4, pp. 295–301, 2010. View at Publisher · View at Google Scholar
  23. R. Hadden, “European federation of neurological societies/peripheral nerve society guideline on management of paraproteinemic demyelinating neuropathies. Report of a joint task force of the European federation of neurological societies and the peripheral nerve society-First revision,” Journal of the Peripheral Nervous System, vol. 15, no. 3, pp. 185–195, 2010. View at Publisher · View at Google Scholar · View at Scopus
  24. “European Federation of Neurological Societies/Peripheral Nerve Society Guideline on management of chronic inflammatory demyelinating polyradiculoneuropathy: report of a joint task force of the European Federation of Neurological Societies and the Peripheral Nerve Society—First Revision,” Journal of the Peripheral Nervous System, vol. 15, no. 1, pp. 1–9, 2010.
  25. K. Kuitwaard and P. A. van Doorn, “Newer therapeutic options for chronic inflammatory demyelinating polyradiculoneuropathy,” Drugs, vol. 69, no. 8, pp. 987–1001, 2009. View at Publisher · View at Google Scholar · View at Scopus
  26. P. D. Donofrio, V. Bril, M. C. Dalakas et al., “Safety and tolerability of immune globulin intravenous in chronic inflammatory demyelinating polyradiculoneuropathy,” Archives of Neurology, vol. 67, no. 9, pp. 1082–1088, 2010. View at Publisher · View at Google Scholar · View at Scopus
  27. L. H. Markvardsen, I. Christiansen, T. Harbo, and J. Jakobsen, “Hemolytic anemia following high dose intravenous immunoglobulin in patients with chronic neurological disorders,” European Journal of Neurology, vol. 21, no. 1, pp. 147–152, 2014. View at Publisher · View at Google Scholar · View at Scopus
  28. D. Paran, Y. Herishanu, O. Elkayam, L. Shopin, and R. Ben-Ami, “Venous and arterial thrombosis following administration of intravenous immunoglobulins,” Blood Coagulation & Fibrinolysis, vol. 16, no. 5, pp. 313–318, 2005. View at Publisher · View at Google Scholar · View at Scopus
  29. A. S. Wolberg, R. H. Kon, D. M. Monroe, and M. Hoffman, “Coagulation factor XI is a contaminant in intravenous immunoglobulin preparations,” The American Journal of Hematology, vol. 65, no. 1, pp. 30–34, 2000. View at Publisher · View at Google Scholar
  30. M. Uchuya, F. Graus, F. Vega, R. René, and J.-Y. Delattre, “Intravenous immunoglobulin treatment in paraneoplastic neurological syndromes with antineuronal autoantibodies,” Journal of Neurology Neurosurgery & Psychiatry, vol. 60, no. 4, pp. 388–392, 1996. View at Publisher · View at Google Scholar · View at Scopus
  31. H. D. Katzberg, V. Rasutis, and V. Bril, “Home IVIG for CIDP: a focus on patient centred care,” The Canadian Journal of Neurological Sciences, vol. 40, no. 3, pp. 384–388, 2013. View at Google Scholar
  32. F. Eftimov, M. Vermeulen, R. J. de Haan, L. H. van den Berg, and I. N. van Schaik, “Subcutaneous immunoglobulin therapy for multifocal motor neuropathy,” Journal of the Peripheral Nervous System, vol. 14, no. 2, pp. 93–100, 2009. View at Publisher · View at Google Scholar · View at Scopus
  33. L. H. Markvardsen, J.-C. Debost, T. Harbo et al., “Subcutaneous immunoglobulin in responders to intravenous therapy with chronic inflammatory demyelinating polyradiculoneuropathy,” European Journal of Neurology, vol. 20, no. 5, pp. 836–842, 2013. View at Publisher · View at Google Scholar · View at Scopus