Research Article
Association of IFN-γ : IL-10 Cytokine Ratio with Nonsegmental Vitiligo Pathogenesis
Table 2
Serum concentrations of IFN-γ, IL-10, and IFN-γ : IL-10 ratio in controls and vitiligo patients.
| | | IFN- in
pg/mL | IL-10
in pg/mL |
IFN- : IL-10
in pg/mL | | | Mean ± SD | Mean ± SD | Mean ± SD |
| | Vitiligo patients (130) | 12.4 ± 3.2 | 9.3 ± 1.7 | 1.3 ± 0.3 | | Controls (150) | 9.9 ± 4.4 | 11.5 ± 5.0 | 0.9 ± 0.7 | | “-” test value | | | | | Clinical variants of vitiligo (%) | | | | | Nondermatomal (44.6) | 12.5 ± 3.2 | 9.7 ± 1.8 | 1.2 ± 0.2 | | Acrofacial (25.4) | 14.4 ± 2.7 | 8.9 ± 1.2 | 1.6 ± 0.3 | | Mucosal (17) | 10.5 ± 3.1 | 9.1 ± 2.1 | 1.1 ± 0.3 | | Focal (13) | 11.0 ± 2.0 | 8.9 ± 1.7 | 1.2 ± 0.1 | | One-way ANOVA “” value | | 0.111 (NS) | | | Disease status (%) | | | | | Stable (36.2) | 11.5 ± 2.7 | 9.3 ± 1.8 | 1.2 ± 0.3 | | Active (63.8) | 13.0 ± 3.3 | 9.3 ± 1.7 | 1.4 ± 0.3 | | “-” test value | | 1 (NS) | | | Family history (%) | | | | | Yes (40) | 12.9 ± 3.4 | 9.1 ± 1.6 | 1.4 ± 0.3 | | No (60) | 12.1 ± 3.1 | 9.4 ± 1.8 | 1.3 ± 0.3 | | “-” test value | 0.1 (NS) | 0.3 (NS) | | | Male patients with SH (%) | | | | | Yes (42) | 14.2 ± 4.1 | 9.9 ± 2.0 | 1.45 ± 0.3 | | No (58) | 10.9 ± 2.8 | 9.1 ± 2.0 | 1.2 ± 0.3 | | “-” test value | | 0.09 (NS) | |
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Note: NS: not significant; , = number of subjects, SD = standard deviation, and SH = social habits.
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