Research Article

Therapeutic Effect of Saponin Rich Fraction of Achyranthes aspera Linn. on Adjuvant-Induced Arthritis in Sprague-Dawley Rats

Table 4

Effect of saponin rich (SR) fraction of Achyranthes aspera on indexes of oxidative stress in liver of arthritic rats.

TreatmentDose (mg/kg)SOD
(U/mL/mg of protein)
CAT
(U/mL/mg of protein)
GSH
(μg/mL/mg of protein)
MDA
(nMol/mL/mg of protein)
Nitric oxide
(μMol/mL/mg of protein)

Control20.44 ± 0.64179.62 ± 5.4221.96 ± 1.327.06 ± 0.51411.78 ± 0.91

FCA Control4.72 ± 0.60#88.83 ± 1.83#6.99 ± 0.76#16.61 ± 0.742#90.72 ± 2.86#

Indo1 10.34 ± 0.50122.98 ± 3.5112.83 ± 0.8210.64 ± 0.10232.22 ± 1.66

SR fraction 50 13.37 ± 0.91127.85 ± 2.8015.65 ± 0.9513.71 ± 0.85840.19 ± 1.79
100 16.75 ± 1.41139.08 ± 2.5415.92 ± 1.219.22 ± 0.73533.81 ± 2.21

Values are presented as mean ± SEM, .
, , and compared with the FCA control group.
# compared with vehicle control.