Research Article

Risk Factors and Adverse Events Poorly Predict Infections and Hypogammaglobulinemia in Granulomatosis with Polyangiitis Patients Receiving Rituximab

Figure 3

Two-dimensional biplot of adverse events using the principal component analysis of the five predictors. CI: chronic infection; CYC: cyclophosphamide cumulative dose; DH: discontinuation due to hypogammaglobulinemia; Gpr: gram of RTX per round; HG: hypogammaglobulinemia defined as total Ig < 6 g/L; Ig: total level of immunoglobulin prior rituximab; Rat: ratio CD4/CD8 prior rituximab; SI: severe infection.