Autoimmune Diseases

The Autoimmune Tautology: From Polyautoimmunity and Familial Autoimmunity to the Autoimmune Genes


Publishing date
15 Mar 2012
Status
Published
Submission deadline
15 Sep 2011

1Center for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, University of El Rosario, Carrera 24 no. 63C-69, Bogota 111221, Colombia

2Systemic Autoimmune Diseases Research Unit, Hospital General Regional No. 36, IMSS, Puebla, PB, Mexico; Departamento de Reumatología, Facultad de Medicina, Benemérita Universidad Autónoma de Puebla, Puebla, PB, Mexico


The Autoimmune Tautology: From Polyautoimmunity and Familial Autoimmunity to the Autoimmune Genes

Description

Autoimmune diseases are chronic conditions initiated by the loss of immunological tolerance to self-antigens and represent a heterogeneous group of disorders that afflict specific target organs or multiple organ systems. The chronic nature of these diseases places a significant burden on the utilization of medical care, direct and indirect economic costs, and quality of life. A significant number of autoimmune disorders are more prevalent in women than men and are among the leading causes of disability for this group of patients.

The fact that autoimmune diseases share several clinical signs and symptoms, physiopathologic mechanisms, and genetic factors has been called autoimmune tautology and indicates that they have a common origin. The multifactorial origin and diversity of expression of autoimmune diseases is referred to the mosaic of autoimmunity. These terms imply that different combinations of the many factors involved in autoimmunity produce varying and unique clinical pictures that represent the wide spectrum of autoimmune diseases.

We invite investigators to submit original research as well review articles that will support and contribute to understand the fact of common origin for autoimmune diseases. We are interested particularly in articles describing similar immunogenetic mechanism, clinical, and physiopathologic evidence of autoimmune diseases demonstrating the autoimmune tautology. Potential topics include, but are not limited to:

  • Why autoimmune diseases affect women more than men
  • Shared pathophysiology in autoimmune diseases
  • Shared subphenotypes among systemic autoimmune diseases
  • How does age at onset influence the outcome of autoimmune diseases?
  • Shared environmental factors in autoimmune diseases
  • The effect of ancestry in autoimmune diseases
  • Common autoimmunity genes
  • Polyautoimmunity
  • Familial autoimmunity
  • Pharmacological agents (biologic and nonbiologic) useful in treating diverse autoimmune diseases

Articles published in this special issue will not be subject to the journal's Article Processing Charges.

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ad/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 297193
  • - Editorial

The Autoimmune Tautology: From Polyautoimmunity and Familial Autoimmunity to the Autoimmune Genes

Juan-Manuel Anaya | Adriana Rojas-Villarraga | Mario García-Carrasco
  • Special Issue
  • - Volume 2012
  • - Article ID 569728
  • - Review Article

Shared HLA Class II in Six Autoimmune Diseases in Latin America: A Meta-Analysis

Paola Cruz-Tapias | Oscar M. Pérez-Fernández | ... | Juan-Manuel Anaya
  • Special Issue
  • - Volume 2012
  • - Article ID 593720
  • - Review Article

Epigenetics and Autoimmune Diseases

Paula Quintero-Ronderos | Gladis Montoya-Ortiz
  • Special Issue
  • - Volume 2012
  • - Article ID 849684
  • - Review Article

Lupus Nephritis: An Overview of Recent Findings

Alberto de Zubiria Salgado | Catalina Herrera-Diaz
  • Special Issue
  • - Volume 2012
  • - Article ID 784315
  • - Review Article

The Biological Significance of Evolution in Autoimmune Phenomena

Carlos A. Cañas | Felipe Cañas
  • Special Issue
  • - Volume 2012
  • - Article ID 792106
  • - Research Article

The Autoimmune Tautology: An In Silico Approach

Ricardo A. Cifuentes | Daniel Restrepo-Montoya | Juan-Manuel Anaya
  • Special Issue
  • - Volume 2012
  • - Article ID 539282
  • - Review Article

Autoimmunity in Rheumatic Diseases Is Induced by Microbial Infections via Crossreactivity or Molecular Mimicry

Taha Rashid | Alan Ebringer
  • Special Issue
  • - Volume 2012
  • - Article ID 254319
  • - Review Article

Introducing Polyautoimmunity: Secondary Autoimmune Diseases No Longer Exist

Adriana Rojas-Villarraga | Jenny Amaya-Amaya | ... | Juan-Manuel Anaya
  • Special Issue
  • - Volume 2012
  • - Article ID 736384
  • - Clinical Study

Spondyloarthropathies in Autoimmune Diseases and Vice Versa

Oscar M. Pérez-Fernández | Rubén D. Mantilla | ... | Juan-Manuel Anaya
  • Special Issue
  • - Volume 2012
  • - Article ID 374635
  • - Research Article

Effect of Selenium on HLA-DR Expression of Thyrocytes

Csaba Balázs | Viktória Kaczur
Autoimmune Diseases
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