Advances in Endocrinology

Research Article

Evaluation of Prepubertal Patients with Suspected Neurosecretory Dysfunction of Growth Hormone Secretion: Diagnostic Steps and Treatment Response

Table 1

Prediagnostic auxological and laboratory data for the two study groups NSD and non-NSD ( values for the differences between the two groups; ANOVA analysis; value < 0,005 for all parameters).


		Age (years)	Weight (kg)	Height (cm)	H-SDS	HV (cm/year)	HV-SDS	dBA (years)	IGF-SDS	IGFBP3-SDS

NSD group		49	47	49	49	49	48	49	47	45
	Mean	9,73	22,94	120,85	−2,82	4,32	−1,03	1,60	−1,81	−0,62
	Median	10,33	22,00	124,40	−2,75	4,40	−1,36	1,67	−2,00	−0,71
	SDS	2,97	8,43	15,83	0,64	1,69	2,04	1,21	0,67	0,90
	Maximum	14,52	43,60	150,0	−1,36	8,60	2,80	5,17	0,18	1,82
	Minimum	3,42	10,06	91,4	−4,18	0,50	−5,37	0,92	−2,96	−2,21

Non-NSD group		41	40	41	41	41	41	40	41	39
	Mean	10,42	24,39	125,18	−2,91	4,76	−0,06	1,82	−1,79	−0,73
	Median	10,33	21,90	122,00	−2,92	4,60	−0,87	2,21	−1,78	−0,70
	SDS	3,00	8,47	16,33	0,98	2,13	2,76	1,68	0,85	0,76
	Maximum	16,00	45,10	159,0	−0,47	12,2	2,90	4,67	0,26	1,01
	Minimum	5,50	12,90	98,5	−6,35	0,60	−3,79	−3,50	−3,02	−2,57

Statistical difference	value	0,275	0,429	0,206	0,612	0,281	0,06	0,468	0,894	0,552