Evaluation of Prepubertal Patients with Suspected Neurosecretory Dysfunction of Growth Hormone Secretion: Diagnostic Steps and Treatment Response

Table 3

Correlations of night profile data with prediagnostic auxological and laboratory data (Spearman’s method). would indicate a level of significance: <0,05; would indicate a level of significance: <0,01. As there were no significant correlations, no asterisks are shown in the tables.

(a)

NSD patients			H-SDS	HV	HV-SDS	Weight	IGF-I-SDS	IGFBP3-SDS	dBA
Spearman-Rho	Number of peaks		,007	,126	,172	,137	,136	,037	−,084
		Significance	,960	,393	,247	,362	,368	,813	,568
	Maximal secretion		,059	−,024	,101	,032	−,200	−,289	,107
		Significance	,691	,869	,499	,832	,182	,057	,468
	Mean secretion		,064	−,013	−,032	−,244	−,105	−,149	0,366
		Significance	,661	,927	,830	,098	,483	,327	,510

(b)

Non-NSD patients			H-SDS	HV	HV-SDS	weight	IGF-I-SDS	IGFBP3-SDS	dBA
Spearman-Rho	Number of peaks		−,010	,121	,062	−,204	−,022	,084	−,224
		Significance	,949	,451	,698	,206	,889	,611	,164
	Maximal secretion		−,137	−,153	−,172	,090	,242	,045	,127
		Significance	,392	,340	,283	,579	,128	,788	,434
	Mean secretion		−,067	,011	,023	,069	,130	,111	−,131
		Significance	,677	,948	,887	,671	,417	,502	,419