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Advances in Hematology
Volume 2009 (2009), Article ID 173439, 3 pages
Case Report

Expansion of T Cells in an Immunocompetent Patient with Acute Toxoplasmosis

1Department of Hematology, Hospital San Pedro, Logroño, La Rioja 26006, Spain
2Department of Hematology, University Clinic, University of Navarra, 31008 Navarra, Spain
3Department of Microbiology, University Clinic, University of Navarra, 31008 Navarra, Spain
4Department of Immunology, University Clinic, University of Navarra, 31008 Navarra, Spain
5Department of Preventive Medicine and Public Health, University of Navarra, 31008 Navarra, Spain

Received 12 October 2008; Revised 12 May 2009; Accepted 16 June 2009

Academic Editor: Luigi Daniele Notarangelo

Copyright © 2009 R. García-Muñoz et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Aliberti, “Host persistence: exploitation of anti-inflammatory pathways by Toxoplasma gondii,” Nature Reviews Immunology, vol. 5, no. 2, pp. 162–170, 2005. View at Publisher · View at Google Scholar
  2. J. G. Montoya and O. Liesenfeld, “Toxoplasmosis,” The Lancet, vol. 363, no. 9425, pp. 1965–1976, 2004. View at Publisher · View at Google Scholar
  3. P. J. Gaddi and G. S. Yap, “Cytokine regulation of immunopathology in toxoplasmosis,” Immunology and Cell Biology, vol. 85, no. 2, pp. 155–159, 2007. View at Publisher · View at Google Scholar
  4. J. G. Montoya, K. E. Lowe, C. Clayberger et al., “Human CD4+ and CD8+ T lymphocytes are both cytotoxic to Toxoplasma gondii-infected cells,” Infection and Immunity, vol. 64, no. 1, pp. 176–181, 1996. View at Google Scholar
  5. E. de Vries, S. de Bruin-Versteeg, W. M. Comans-Bitter et al., “Longitudinal survey of lymphocyte subpopulations in the first year of life,” Pediatric Research, vol. 47, no. 4, pp. 528–537, 2000. View at Google Scholar
  6. S. Vasto, G. Colonna-Romano, A. Larbi, A. Wikby, C. Caruso, and G. Pawelec, “Role of persistent CMV infection in configuring T cell immunity in the elderly,” Immunity and Ageing, vol. 4, p. 2, 2007. View at Publisher · View at Google Scholar
  7. Y. Le Priol, D. Puthier, C. Lécureuil et al., “High cytotoxic and specific migratory potencies of senescent CD8+CD57+ cells in HIV-infected and uninfected individuals,” The Journal of Immunology, vol. 177, no. 8, pp. 5145–5154, 2006. View at Google Scholar
  8. I. Sada-Ovalle, L. Torre-Bouscoulet, R. Valdez-Vazquez, S. Martinez-Cairo, E. Zenteno, and R. Lascurain, “Characterization of a cytotoxic CD57+ T cell subset from patients with pulmonary tuberculosis,” Clinical Immunology, vol. 121, no. 3, pp. 314–323, 2006. View at Publisher · View at Google Scholar
  9. R. D. Kovaiou, B. Weinberger, and B. Grubeck-Loebenstein, “Aging and the immune system,” in Clinical Immunology Principles and Practice, R. R. Rich, T. A. Fleisher, W. T. Shearer, H. W. Schroeder Jr., A. J. Frew, and C. M. Weyland, Eds., pp. 739–747, Mosby Elsevier, St. Louis, Miss, USA, 3rd edition, 2008. View at Google Scholar
  10. N. Khan, A. Hislop, N. Gudgeon et al., “Herpesvirus-specific CD8 T cell immunity in old age: cytomegalovirus impairs the response to a coresident EBV infection,” The Journal of Immunology, vol. 173, p. 7481, 2004. View at Google Scholar
  11. E. Bandrés, J. Merino, B. Vázquez et al., “The increase of IFN-? production through aging correlates with the expanded CD8+highCD28-CD57+ subpopulation,” Clinical Immunology, vol. 96, no. 3, pp. 230–235, 2000. View at Publisher · View at Google Scholar
  12. L. K. Chong, R. J. Aicheler, S. Llewellyn-Lacey, P. Tomasec, P. Brennan, and E. C. Y. Wang, “Proliferation and interleukin 5 production by CD8hiCD57+ T cells,” European Journal of Immunology, vol. 38, no. 4, pp. 995–1000, 2008. View at Publisher · View at Google Scholar
  13. Y. Zhang and E. Y. Denkers, “Protective role for interleukin-5 during chronic Toxoplasma gondii infection,” Infection and Immunity, vol. 67, no. 9, pp. 4383–4392, 1999. View at Google Scholar