Vitamin E and N-Acetylcysteine as Antioxidant Adjuvant Therapy in Children with Acute Lymphoblastic Leukemia

Table 2

Toxic hepatitis in both leukemia groups during phases I and II of chemotherapy.

	Group I (𝑛=20)		Group II (𝑛=20)		P
	No	%	No	%
After phase I	6	30.0	12	60.0	.02
After phase II	8	40.0	20	100.0	.001

Toxic hepatitis is diagnosed by elevation of liver enzymes 2-3 folds after chemotherapy with exclusion of viral hepatitis and normalization of these enzymes when chemotherapy was temporary suspended. Significance of Chi square test if 𝑃<.05.