Advances in Hematology / 2009 / Article / Tab 1

Research Article

ETV6-RUNX1 Rearrangement in Tunisian Pediatric B-Lineage Acute Lymphoblastic Leukemia

Table 1

Summary of patients with abnormal FISH findings.

PatientsAge/sex (years)Karyotype (number of cells)FISH signals (No.) % of cells
ETV6RUNX1ETV6-RUNX1 fusion

113/M46, XY[ ]012 15
22/M46, XY[ ]011 16
35/M46, XY, del(20)(p12)[ ]/46, XY[ ]11217
46/M46, XY[ ]121 25
53/F46, X, X, add(3)(q27), mar[ ]/46, XX[ ]330 18
615/F48, XX, t(2;11)(p12;q23), 20, 21[ ]230 24
713/M46, XY, 16, mar[ ]/46, XX[ ]23/40 14
82/F46, XX[ ]240 19
97/M46, XY[ ]111 14
104/F46, XX[ ]111 23
1114/M46, XY[ ]11132
124/F46, XX[ ]11117
134/F46, XX[ ]11115
145/M46, XY[ ]121 44
153.5/F46, XX[ ]11122
1614/M46, XX, , dic(1;16)(p31;p13)X2, , mar[ ]230 14
1713/M47, XXY, del(12)(p12 p13)[ ]/47, XXY[ ]230 16
187/F47, XX, 5[ ]/46, XX[ ]111 17
198/M46, XY[ ]11127
204/FNo metaphases111 41
4/F46, XX[ ]111 18
223/M46, XY[ ]11 1 22
231.2/M46, XY[ ]23 0 14

case harbored two distinct clones: one with only the ETV6/RUNX1 rearrangement and the second (9% of cells) with an extra signal of RUNX1 gene.
No: number.

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