Promyelocytic Sarcoma of the Spine: A Case Report and Review of the Literature

Table 1

Clinical features of patients with MS in APL.

References	No. cases	disease status	Time since	Site of involvement
			diagnosis/EMD relapse (months)
Fukushima et al. [31]	1	onset		cerebellum + hematological
Worch et al. [32]	1	onset		lytic lesions of humerus, tibia, femur + molecular hematological
Ajarim et al. [33]	1	onset		thymus + hematological
Savranlar et al. [34]	1	onset		thoracic-epidural
Brown et al. [35]	1	onset		optic nerve + hematological
Agarwal et al. [36]	1	relapse	31	hip + hematological
Disel et al. [37]	1	relapse	9	pleura
Tsimberodou et al. [30]	1	relapse	36	thoracic spine
Specchia et al. [38]	1	relapse	NA	lung + hematological
	3	relapse	155	mastoid + hematological
Latagliata et al. [39]			71	mastoid + mol hematological
			61	mastoid
	3	relapse	7	subcutaneous nodules at sternal manubrium + wrist at level of the radial artery pulse + site of intravenous catheter scar+ mol hematological
Sanz et al. [40]			6	subcutaneous nodules at jugular catheter scar + wrists at level of the radial artery pulse + molecular hematological
			32	sternal manubrium + subcutaneous nodule + antecubital fossa
Magliulo et al. [41]	1	relapse	24	external auditory canal+ mol hematological
Nasilowska-Adamska et al. [42]	1	relapse	21	pleura, heart and pericardium
Slavecheva et al. [43]	1	relapse	120	lymph node
Kai et al. [44]	1	relapses	NA	4 time at different sites
Tobita et al. [45]	1	relapses	NA	1st and 2nd external auditory canal
Forrest et al. [46]	1	relapse	1st 48-2nd 24	1st testicular -2nd retroperitoneal nodes, psoas muscle and skin
Skarin et al. [47]	1	relapse	8	CNS + hematologic
Leoni et al. [48]	2	relapse	NA	(1) central nervous system + middle ear + lymph nodes.
				(2) skin + lymph nodes
Ammatuna et al. [49]	1	relapse	NA	1st and 2nd -scalp + mol hematological 3rd mol hematological + breast
Breccia et al. [50]	7	relapse	5 from CR	(1) left auricular canal + mastoid + mol hematological
			69	(2) left mastoid + mol hematological
			58	(3) left mastoid
			9	(4) left mastoid + hematologic
			12	(5) left mastoid + hematologic
			64	(6) right auricular canal
			6 from 2nd CR	(7) right mastoid + CNS + mol hematological

NA: not available; mol: molecular; CR: complete remission;