What Role for Angiogenesis in Childhood Acute Lymphoblastic Leukaemia?

Table 2

Expression of endostatin, vascular endothelial growth factor (VEGF), and basic fibroblast growth factor (bFGF) by lymphoblasts (RT-PCR) in a group of 24 patients. The protein was measured by ELISA method in 28 patients and was expressed in half of the cases studied, for endostatin and VEGF. We found no expression of bFGF by the lymphoblasts, neither bFGF mRNA nor protein expression [29].

	mRNA (RT-PCR)	Protein (ELISA)
Endostatin	19/24	14/28
VEGF	24/24	6/12
bFGF	0	0