Research Article
Predicting the Kinetic Properties Associated with Redox Imbalance after Oxidative Crisis in G6PD-Deficient Erythrocytes: A Simulation Study
Table 1
Hematological and kinetic parameters of G6PD-deficient patients (obtained from [
19,
20]).
| Patient | Reticulocytes (%) | Half-life (days) | (M/s) | (μM) | (μM) | (μM) | (μM) | (μM) |
| Patient 1 | 40 | 2.5 | 1.1 | 152 | 3.8 | 0.62 | 180 | 520 | Patient 2 | 2 | — | 36.7 | 140 | 115 | 33.6 | 4687 | 8515 | Patient 3 | 2 | 22.5 | 0.8 | 7 | 4.1 | 8.9 | 952 | 1071 | Patient 4 | 22 | — | 0.8 | 43 | 155 | 56 | 11000 | 35000 | Patient 5 | 2 | 20.0 | 37.1 | 57 | 30.5 | 3.7 | 5016 | 5507 | Patient 6 | 15 | 7.2 | 14.5 | 66 | 3.5 | 1.1 | 212 | 532 | Patient 7 | 10 | — | 8.9 | 80 | 3.6 | 1 | 125 | 586 | Patient 8 | 4 | — | 0.8 | 68 | 1.4 | 0.9 | 500 | 2000 | Patient 9 | 30 | 5.0 | 0.6 | 40 | 4.8 | 6.9 | 314 | 3784 | Patient 10 | 15 | — | 18.9 | 79 | 3 | 4.1 | 407 | 2200 |
| Control | 1 | 27 | 64 | 67 | 3.7 | 3.1 | 749 | 2289 |
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