Steroid-Refractory Acute GVHD: Predictors and Outcomes

Table 1

Patients and transplant characteristics.

Characteristic	Value (%)
No. of patients	287
Patient age
Median, y (range)	45	(19–72)
Older than 40 y	138	(48)
40 y or younger	149	(52)
Median no. of prior chemotherapy lines (range)	2	(0–9)
Donor/patient sex mismatch
Female Donor/Male Patient	73	(25)
Other	214	(75)
Diagnosis
Lymphoid	163	(57)
Myeloid	100	(35)
Multiple myeloma	8	(3)
Solid tumor	4	(1)
Other	12	(4)
Disease status at transplantation
Not in remission	188	(66)
Remission	99	(34)
Donor type
Matched	251	(88)
Mismatched	36	(12)
Cell source
Peripheral Blood	126	(44)
Bone Marrow	161	(56)
Conditioning regimen
Reduced intensity	102	(35.5)
High-dose chemotherapy	137	(50.5)
High-dose chemotherapy/TBI	48	(13.9)