Advances in Hematology / 2012 / Article / Fig 5

Research Article

EBV Reactivation and Chromosomal Polysomies: Euphorbia tirucalli as a Possible Cofactor in Endemic Burkitt Lymphoma

Figure 5

To assess whether multiple MYC signals relied on MYC gene amplification or on chromosomal 8 polyploidy, a centromeric probe for chromosome 8 was used. Our results indicated the presence of multiple signals for chromosome 8 in cells treated with E. tirucalli, consistent with a polysomy of chromosome 8. Arrows indicate cells with multiple chromosome 8 and MYC signals.

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