Categories of posttransplant lymphoproliferative disorders.
(1) Early lesions
(a) Reactive plasmacytic hyperplasia
(b) Infectious mononucleosis-like lesions
(2) Polymorphic PTLD
(3) Monomorphic PTLD (classified according to lymphoma they resemble)
B-cell neoplasms
(a) Diffuse large B-cell lymphoma (DLBCL)
(b) Burkitt’s lymphoma
(c) Plasma cell myeloma
(d) Plasmacytoma-like lesions
(e) Others*
T-cell neoplasms
(a) Peripheral T-cell lymphoma not otherwise specified
(b) Hepatosplenic T-cell lymphoma
(c) Others
(4) Classical Hodgkin’s lymphoma-type (HL-PTLD) and HL-like PTLD**
*Indolent small B-cell lymphomas developing in transplant recipient are not included among the PTLD.
**HL-like PTLDs are better categorized either as a polymorphic or monomorphic PTLD based on the overall morphology.
