Review Article

HIV-Associated Hodgkin's Lymphoma: Prognosis and Therapy in the Era of cART

Figure 1

Representative images of mixed cellularity HIV-associated classical Hodgkin's lymphoma. (a) High-power H and E image shows a prominent Hodgkin Reed Sternberg (HRS) cell surrounded by a mixed population of lymphocytes, eosinophils, granulocytes, and histiocytes. (b) Low-power view of CD30 immunohistochemistry highlights the rare large HRS cells, as does in-situ hybridization for EBER (c), reflecting the Epstein-Barr virus (EBV) infection of HRS cells.
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