Anaplastic Lymphoma Kinase-Positive Large B-Cell Lymphoma: An Underrecognized Aggressive Lymphoma

Figure 2

ALK+ LBCL immunohistochemical profile. All tumors are positive for ALK (a) and CD138 (b). CD20 (c) is almost always negative, but MUM-1 (d) is frequently positive. IgA is often expressed (e). EMA can show focal to diffuse positivity (f). All microphotographs are 400x.

(a)

(b)

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(d)

(e)

(f)