Advances in Hematology / 2012 / Article / Tab 4

Research Article

DNMT3A Mutations in Patients with Acute Myeloid Leukemia in South Brazil

Table 4

Description of somatic mutations found in gene DNMT3A.

Patient
identification
MutationAllelic changeExonType of
mutation
FAB
subtype
PCRRisk groupKaryotype

39D748NG>A19Missense M1NegativeIntermediateNormal
79R882HG>A23Missense M1NegativeIntermediateTrisomy (8)(9)
4R882HG>A23Missense M3NegativeIntermediateNormal
70R882HG>A23Missense M2NegativeIntermediateNormal
41H896*A>G23Silent M3PML/RARαFavorablet(15;17)
78R973QG>A23Missense Negative

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