DNMT3A Mutations in Patients with Acute Myeloid Leukemia in South Brazil
Table 5
Clinical characteristics of patients with acute myeloid leukemia with or without DNMT3A mutations.
Characteristics
Number of pts (%) DNMT3A mutated
Number of pts (%) DNMT3A not mutated
Age (median)
40.2
44.8
0.56
Sex
Male
50%
59.3%
0.68
Female
50%
40.7%
Subtype FAB
M0
0%
7.2%
M1
60%
18.8%
M2
20%
30.4%
0.56
M3
20%
20.3%
M4
0%
18.8%
M5
0%
1.4%
Not M3
0%
2.9%
Risk groups
Favorable
20%
29.8%
Intermediate
80%
59.6%
1.000
Unfavorable
0%
10.5%
Leukocytes (×103) (median)
20.67
6.41
0.28
Death
50%
51.4%
1.000
Relapses
50%
30.9%
0.58
Refractory
20%
19.1%
0.96
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