Research Article

Bone Marrow and Peripheral Blood AML Cells Are Highly Sensitive to CNDAC, the Active Form of Sapacitabine

Figure 3

Apoptosis analysis of HL-60 and THP-1 cells. Plots represent distribution of □% early and ■% late apoptotic (a) HL-60 and (b) THP-1 cells treated with ara-C, CNDAC, or mitoxantrone as determined by 7-AAD/Annexin V staining. Cells were plated at 0.5 × 106 cells/mL, in triplicate, and drug-treated for 3, 4, 5, and 6 days. The entire bar represents total dead cells.
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