Table of Contents Author Guidelines Submit a Manuscript
Advances in Hematology
Volume 2013, Article ID 195746, 4 pages
http://dx.doi.org/10.1155/2013/195746
Research Article

Approach to Management of Thrombotic Thrombocytopenic Purpura at University of Cincinnati

1Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
2Division of Hematology and Oncology, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
3Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
4Department of Hematology and Oncology, Baylor College of Medicine, Houston, TX 76706, USA
5Hoxworth Blood Center, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA

Received 23 September 2013; Revised 14 November 2013; Accepted 28 November 2013

Academic Editor: Estella M. Matutes

Copyright © 2013 N. Abdel Karim et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. E. L. Amorosi and J. E. Ultmann, “Thrombotic thrombocytopenic purpura: report of 16 cases and review of the literature,” Medicine, vol. 45, no. 2, pp. 139–160, 1966. View at Google Scholar
  2. G. Remuzzi and S. Garella, “HUS and TTP: variable expression of a single entity,” Kidney International, vol. 32, no. 2, pp. 292–308, 1987. View at Google Scholar · View at Scopus
  3. H. von Baeyer, “Plasmapheresis in thrombotic microangiopathy-associated syndromes: review of outcome data derived from clinical trials and open studies,” Therapeutic Apheresis, vol. 6, no. 4, pp. 320–328, 2002. View at Google Scholar · View at Scopus
  4. J. A. Kremer Hovinga, S. K. Vesely, D. R. Terrell, B. Lämmle, and J. N. George, “Survival and relapse in patients with thrombotic thrombocytopenic purpura,” Blood, vol. 115, no. 8, pp. 1500–1511, 2010. View at Publisher · View at Google Scholar · View at Scopus
  5. G. A. Rock, K. H. Shumak, N. A. Buskard et al., “Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura,” The New England Journal of Medicine, vol. 325, no. 6, pp. 393–397, 1991. View at Publisher · View at Google Scholar
  6. C. L. Balduini, L. Gugliotta, M. Luppi et al., “High versus standard dose methylprednisolone in the acute phase of idiopathic thrombotic thrombocytopenic purpura: a randomized study,” Annals of Hematology, vol. 89, no. 6, pp. 591–596, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. K. H. Shumak, G. A. Rock, and R. C. Nair, “Late relapses in patients successfully treated for thrombotic thrombocytopenic purpura,” Annals of Internal Medicine, vol. 122, no. 8, pp. 569–572, 1995. View at Google Scholar · View at Scopus
  8. J. M. Durand, P. Lefevre, G. Kaplanski, and J. Soubeyrand, “Ineffectiveness of high-dose intravenous gammaglobulin infusion in thrombotic thrombocytopenic purpura,” American Journal of Hematology, vol. 42, no. 2, article 234, 1993. View at Google Scholar · View at Scopus
  9. J. M. Durand, P. Lefevre, G. Kaplanski, H. Telle, and J. Soubeyrand, “Vincristine for thrombotic thrombocytopenia purpura,” The Lancet, vol. 340, no. 8825, pp. 977–978, 1992. View at Google Scholar · View at Scopus
  10. N. T. J. O'Connor, M. J. O'Shea, and L. F. Hill, “Vincristine for thrombotic thrombocytopenic purpura,” The Lancet, vol. 340, no. 8817, p. 490, 1992. View at Publisher · View at Google Scholar · View at Scopus
  11. M. Udvardy and K. Rak, “Cyclophosphamide for chronic relapsing thrombotic thrombocytopenic purpura,” The Lancet, vol. 336, no. 8729, pp. 1508–1509, 1990. View at Publisher · View at Google Scholar · View at Scopus
  12. M. A. Crowther, N. Heddle, C. P. M. Hayward, T. Warkentin, and J. G. Kelton, “Splenectomy done during hematologic remission to prevent relapse in patients with thrombotic thrombocytopenic purpura,” Annals of Internal Medicine, vol. 125, no. 4, pp. 294–296, 1996. View at Google Scholar · View at Scopus
  13. M. A. Rizvi, S. K. Vesely, J. N. George et al., “Complications of plasma exchange in 71 consecutive patients treated for clinically suspected thrombotic thrombocytopenic purpura-hemolytic-uremic syndrome,” Transfusion, vol. 40, no. 8, pp. 896–901, 2000. View at Publisher · View at Google Scholar · View at Scopus
  14. V. McDonald, K. Manns, I. J. Mackie, S. J. Machin, and M. A. Scully, “Rituximab pharmacokinetics during the management of acute idiopathic thrombotic thrombocytopenic purpura,” Journal of Thrombosis and Haemostasis, vol. 8, no. 6, pp. 1201–1208, 2010. View at Publisher · View at Google Scholar · View at Scopus
  15. J. Goyal, J. Adamski, J. L. Lima, and M. B. Marques, “Relapses of thrombotic thrombocytopenic purpura after treatment with rituximab,” Journal of Clinical Apheresis, 2013. View at Publisher · View at Google Scholar