Research Article

RhD Specific Antibodies Are Not Detectable in HLA-DRB1 Mice Challenged with Human RhD Positive Erythrocytes

Table 1

Amino acid sequence and properties of the RhD peptides synthesized.

Peptide #Amino acidsSequenceM.W.Sequence identity with RhCENet charge
(pH 7)

134–46YDASLEDQKGLVAC*1510.68100%−1
2228–238LRSPIERKNAVC*1384.6682%3
3350–358DTVGAGNGMRR 1235.4067%2
497–111FLSQFPSGKVVITLFC*1785.1793%2

A cysteine was added at the C-terminus for conjugation purposes.
aTwo arginines (R) were added to peptide 3 to increase its solubility.