Determinants of Overall and Progression-Free Survival of Nigerian Patients with Philadelphia-Positive Chronic Myeloid Leukemia

Table 3

Univariate analysis of all 272 patients’ characteristics as predictors of overall and progression-free survival.

Parameters at recruitment	Number	OS	PFS
Sex: male/female	171/101	0.041	0.005
Age (years)
≤30/>30	68/204	ns	ns
≤38/>38	134/138	ns	ns
≤50/>50	207/65	ns	ns
Hematocrit at diagnosis (%)
≤30/>30	110/162	0.069	0.009
≤35/>35	165/107	0.078	0.022
WBC at diagnosis (×10^9/L)
≤100/>100	144/128	ns	ns
Platelet count (×10^9/L)
≤250/>250	144/128	ns	ns
≤350/>350	187/85	ns	ns
Disease phase at diagnosis
CP/AP/BP	205/54/5	0.078	ns
CP/Adv	205/59	0.030	ns
Spleen (cm, BCM)
≤10/>10	113/159	ns	0.048

values in bold type are significant; those in regular type are close to significance. The variables with better outcomes are written first. OS, overall survival; PFS, progression-free survival; BCM, below the costal margin; ns, not significant; NA, not applicable.