Efficacy and Safety of Manual Partial Red Cell Exchange in the Management of Severe Complications of Sickle Cell Disease in a Developing Country

Table 2

Evaluation of the blood count parameters after one RCE and hemoglobin fractions after 2 consecutive RCE performed the day of admission.

Parameters	Values				Mean variation
	Baseline		Final
	Mean	95% CI	Mean	95% CI
Blood count before and after one RCE ()
Red cells count (10^12/L)	3,1	2,9–3,3	3,3	3,1–3,4	+0,2
Hemoglobin rate (g/dL)	8,9	8,6–9,1	10,3	8,5–12,2	+1,4
Hematocrit (%)	26,2	24,7–27,8	30,6	23,3–37,6	+4,4
White cells count (10^9/L)	11,5	10,7–12,2	11,6	10,4–12,7	+0,1
Platelets count (10^9/L)	443	414–473	433	401–475	−10
Fractions of hemoglobin before and after 2 RCE performed the day of admission ()
Hemoglobin S (%)	84,8	80,5–89	24,8	20,6–32	−60
Hemoglobin A (%)	0	—	64	58–70	+64
Hemoglobin F (%)	10,2	8,0–12,5	6	3,0–7,5	−4,2
Hemoglobin A2 (%)	3,3	2,9–3,7	2,3	1,9–3,0	−1